NCCN Policy Summit Explores AI's Impact on Cancer Treatment

Published Date : 09/09/2025 

The National Comprehensive Cancer Network (NCCN) hosted a Policy Summit to explore the current and future roles of artificial intelligence (AI) in cancer care, with experts highlighting both the opportunities and challenges. 

Newswise — WASHINGTON, D.C. [September 9, 2025] — Today, the National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers devoted to patient care, research, and education—hosted a Policy Summit exploring where artificial intelligence (AI) currently stands as a tool for improving cancer care, and where it may be going in the future. Subject matter experts, including patients and advocates, clinicians, and policymakers, weighed in on where they saw emerging success and also reasons for concern.

Travis Osterman, DO, MS, FAMIA, FASCO, Director of Cancer Clinical Informatics, Vanderbilt-Ingram Cancer Center—a member of the NCCN Digital Oncology Forum—delivered a keynote address, stating: “Because of AI, we are at an inflection point in how technology supports the delivery of care to our patients with cancer. Thoughtful regulation can help us integrate these tools into everyday practice in ways that improve care delivery and support oncology practices. The decisions we make now will determine how AI innovations serve our patients and impact clinicians for years to come.”

Many speakers took a cautiously optimistic tone on AI, rooted in pragmatism. “AI isn’t the future of cancer care… it’s already here, helping detect disease earlier, guide personalized treatment, and reduce clinical burdens,” said William Walders, Executive Vice President, Chief Digital and Information Officer, The Joint Commission. “To fully realize the promise of AI in oncology, we must implement thoughtful guardrails that not only build trust but actively safeguard patient safety and uphold the highest standards of care. At Joint Commission, our mission is to shape policy and guidance that ensures AI complements, never compromises, the human touch. These guardrails are essential to prevent unintended consequences and to ensure equitable, high-quality outcomes for all.”

Panelists noted the speed at which AI models are evolving. Some compared its potential to previous advances in care, such as the leap from paper to electronic medical records. Many expressed excitement over the possibilities it represents for improving efficiency and helping to support an overburdened oncology workforce and accelerate the pursuit of new cures.

“Artificial intelligence is transforming every industry, and oncology is no exception,” stated Jorge Reis-Filho, MD, PhD, FRCPath, Chief AI and Data Scientist, Oncology R&D, AstraZeneca. “With the advent of multimodal foundation models and agentic AI, there are unique opportunities to propel clinical development, empowering researchers and clinicians with the ability to generate a more holistic understanding of disease biology and develop the next generation of biomarkers to guide decision making.”

“AI has enormous potential to optimize cancer outcomes by making clinical trials accessible to patients regardless of their location and by simplifying complex trial processes for patients and research teams alike. I am looking forward to new approaches for safe evaluation and implementation so that we can effectively and responsibly use AI to gain maximum insight from every piece of patient data and drive progress,” commented Danielle Bitterman, MD, Clinical Lead for Data Science/AI, Mass General Brigham. She continued: “As AI becomes integrated into clinical practice, stronger collaborations between oncologists and computer scientists will catalyze advances and will be key to directly addressing the most urgent challenges in cancer care.”

Regina Barzilay, PhD, School of Engineering Distinguished Professor for AI and Health, MIT, expressed her concern that adoption may not be moving quickly enough: “AI-driven diagnostics and treatment has potential to transform cancer outcomes. Unfortunately, today, these tools are not utilized enough in patient care. Guidelines could play a critical role in changing this status quo.” She illustrated some specific AI technologies that she believes are ready to be implemented into patient care and asserted her wishes for keeping up with rapidly progressing technology.

Some of the panel participants raised issues about the potential challenges from AI adoption, including:

- How to implement quality control, accreditation, and fact-checking in a way that is fair and not burdensome

- How to determine appropriate governmental oversight

- How medical and technology organizations can work together to best leverage the expertise of both

- How to integrate functionality across various platforms

- How to avoid increasing disparities and technology gaps

- How to account for human error and bias while maintaining the human touch

“Many similar problems have been solved in different application environments,” concluded Allen Rush, PhD, MS, Co-Founder and Board Chairman, Jacqueline Rush Lynch Syndrome Cancer Foundation. “This will take teaming up with non-medical industry experts to find the best tools, fine-tune them, and apply ongoing learning. We need to ask the right questions and match them with the right AI platforms to unlock new possibilities for cancer detection and treatment.”

The topic of AI and cancer care was also featured in a plenary session during the NCCN 2025 Annual Conference. Visit NCCN.org/conference to view that session and others via the NCCN Continuing Education Portal. Next up, on Tuesday, December 9, 2025, NCCN is hosting a Patient Advocacy Summit on addressing the unique cancer care needs of veterans and first responders. Visit NCCN.org/summits to learn more and register.

About the National Comprehensive Cancer Network

The National Comprehensive Cancer Network® (NCCN®) is marking 30 years as a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to defining and advancing quality, effective, equitable, and accessible cancer care and prevention so all people can live better lives. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) provide transparent, evidence-based, expert consensus-driven recommendations for cancer treatment, prevention, and supportive services; they are the recognized standard for clinical direction and policy in cancer management and the most thorough and frequently-updated clinical practice guidelines available in any area of medicine. The NCCN Guidelines for Patients® provide expert cancer treatment information to inform and empower patients and caregivers, through support from the NCCN Foundation®. NCCN also advances continuing education, global initiatives, policy, and research collaboration and publication in oncology. Visit NCCN.org for more information. 

Frequently Asked Questions (FAQS): 

Q: What is the NCCN Policy Summit?

A: The NCCN Policy Summit is an event hosted by the National Comprehensive Cancer Network (NCCN) to explore the current and future roles of artificial intelligence (AI) in cancer care. It brings together experts, including patients, advocates, clinicians, and policymakers, to discuss the opportunities and challenges of AI in oncology.

Q: How can AI improve cancer care?

A: AI can improve cancer care by helping detect disease earlier, guiding personalized treatment, reducing clinical burdens, and making clinical trials more accessible and efficient. It also has the potential to simplify complex trial processes for patients and research teams.

Q: What are some concerns about AI in cancer care?

A: Concerns about AI in cancer care include the need for quality control, appropriate governmental oversight, integration of functionality across platforms, avoiding disparities and technology gaps, and maintaining the human touch while accounting for human error and bias.

Q: What role do guidelines play in AI adoption?

A: Guidelines can play a critical role in ensuring the responsible and effective adoption of AI in cancer care. They can help standardize the use of AI tools, build trust, and safeguard patient safety and the highest standards of care.

Q: What is the NCCN's mission?

A: The National Comprehensive Cancer Network® (NCCN®) is dedicated to defining and advancing quality, effective, equitable, and accessible cancer care and prevention so all people can live better lives. They provide transparent, evidence-based, expert consensus-driven recommendations for cancer treatment, prevention, and supportive services. 

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